PIP5K1A

PIP5K1A
Identifiers
Aliases	PIP5K1A, phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
External IDs	OMIM: 603275; MGI: 107929; HomoloGene: 93492; GeneCards: PIP5K1A; OMA:PIP5K1A - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	151,249,536 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	95,106,930 bp
RNA expression pattern
	Top expressed in
	right testis; ; epithelium of colon; ; left testis; ; sural nerve; ; Achilles tendon; ; gastric mucosa; ; skin of leg; ; left uterine tube; ; skin of abdomen; ; islet of Langerhans;
	Top expressed in
	gastrula; ; Rostral migratory stream; ; decidua; ; olfactory tubercle; ; cumulus cell; ; CA3 field; ; dentate gyrus; ; pineal gland; ; dentate gyrus of hippocampal formation granule cell; ; primary motor cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; 1-phosphatidylinositol-4-phosphate 5-kinase activity; kinase activity; kinase binding; protein binding; phosphatidylinositol phosphate kinase activity; ATP binding; 1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-5-kinase activity; phosphatidylinositol-3,4-bisphosphate 5-kinase activity; 1-phosphatidylinositol-3-phosphate 4-kinase activity;
Cellular component	nuclear speck; mRNA cleavage and polyadenylation specificity factor complex; cell projection; membrane; focal adhesion; ruffle; plasma membrane; nucleoplasm; ruffle membrane; nucleus; lamellipodium; cytoplasm; cytosol;
Biological process	fibroblast migration; actin cytoskeleton reorganization; phosphatidylinositol metabolic process; activation of GTPase activity; phosphorylation; keratinocyte differentiation; focal adhesion assembly; phospholipid biosynthetic process; phagocytosis; cell chemotaxis; glycerophospholipid metabolic process; ruffle assembly; cell migration; signal transduction; phosphatidylinositol phosphate biosynthetic process; regulation of phosphatidylinositol 3-kinase signaling; phosphatidylinositol biosynthetic process; protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	8394
	18720
	ENSG00000143398
	ENSMUSG00000028126
	Q99755
	P70182
	NM_001135636; NM_001135637; NM_001135638; NM_003557; NM_001330689
	NM_001293707; NM_008847
	NP_001129108; NP_001129109; NP_001129110; NP_001317618; NP_003548
	NP_001280636; NP_032873
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha is an enzyme that in humans is encoded by the PIP5K1A gene.