PIP5K1B

PIP5K1B
Identifiers
Aliases	PIP5K1B, MSS4, STM7, phosphatidylinositol-4-phosphate 5-kinase type 1 beta
External IDs	OMIM: 602745; MGI: 107930; HomoloGene: 100644; GeneCards: PIP5K1B; OMA:PIP5K1B - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	69,009,176 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	24,533,236 bp
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; jejunal mucosa; ; mucosa of ileum; ; mucosa of colon; ; mucosa of sigmoid colon; ; rectum; ; duodenum; ; cardiac muscle tissue of right atrium; ; gonad; ; myocardium of left ventricle;
	Top expressed in
	choroid plexus of fourth ventricle; ; saccule; ; Epithelium of choroid plexus; ; parotid gland; ; retinal pigment epithelium; ; otic placode; ; crypt of lieberkuhn of small intestine; ; otic vesicle; ; granulocyte; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein binding; phosphatidylinositol phosphate kinase activity; ATP binding; kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-kinase activity; 1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-3-phosphate 4-kinase activity; phosphatidylinositol-3,4-bisphosphate 5-kinase activity;
Cellular component	uropod; membrane; endomembrane system; cytosol;
Biological process	phosphatidylinositol phosphate biosynthetic process; phosphatidylinositol metabolic process; phosphorylation; phosphatidylinositol biosynthetic process; regulation of phosphatidylinositol 3-kinase signaling;
	Sources:Amigo / QuickGO
Orthologs
	8395
	18719
	ENSG00000107242
	ENSMUSG00000024867
	O14986
	P70181
NM_001031687; NM_001278253; NM_003558; NM_001376036; NM_001376037;
	NM_001376039; NM_001376040; NM_001376041
	NM_008846
NP_001265182; NP_003549; NP_001362965; NP_001362966; NP_001362968;
	NP_001362969; NP_001362970
	NP_032872
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylinositol-4-phosphate 5-kinase type-1 beta is an enzyme that in humans is encoded by the PIP5K1B gene.

Abnormal silencing of the PIP5K1B gene contributes to the cytoskeletal defects seen in Friedreich's ataxia.