PJA2

PJA2
Identifiers
Aliases	PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2
External IDs	MGI: 2159342; HomoloGene: 32233; GeneCards: PJA2; OMA:PJA2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	109,409,974 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	64,638,911 bp
RNA expression pattern
	Top expressed in
	tail of epididymis; ; postcentral gyrus; ; frontal pole; ; Achilles tendon; ; Brodmann area 46; ; prefrontal cortex; ; orbitofrontal cortex; ; Pons; ; caput epididymis; ; superior vestibular nucleus;
	Top expressed in
	interventricular septum; ; medial dorsal nucleus; ; dorsal striatum; ; temporal lobe; ; olfactory tubercle; ; globus pallidus; ; inferior colliculi; ; facial motor nucleus; ; Region I of hippocampus proper; ; nucleus accumbens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase A regulatory subunit binding; ubiquitin-protein transferase activity; protein kinase A catalytic subunit binding; ubiquitin protein ligase activity; metal ion binding; transferase activity; protein binding;
Cellular component	Golgi membrane; postsynaptic density; membrane; endoplasmic reticulum; synapse; plasma membrane; cytoplasm; cell junction; postsynaptic membrane; Golgi apparatus; intermediate filament cytoskeleton; endoplasmic reticulum membrane;
Biological process	hippo signaling; regulation of protein kinase A signaling; long-term memory; protein ubiquitination; inflammatory response; positive regulation of toll-like receptor 2 signaling pathway; regulation of macrophage activation; innate immune response; positive regulation of JNK cascade; positive regulation of p38MAPK cascade;
	Sources:Amigo / QuickGO
Orthologs
	9867
	224938
	ENSG00000198961
	ENSMUSG00000024083
	O43164
	Q80U04
	NM_014819
	NM_001025309; NM_144859
	NP_055634
	NP_001020480; NP_659108
	Wikidata
View/Edit Human	View/Edit Mouse

E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene.