Plakophilin-4

PKP4
Identifiers
Aliases	PKP4, p0071, plakophilin 4
External IDs	OMIM: 604276; MGI: 109281; HomoloGene: 2689; GeneCards: PKP4; OMA:PKP4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	158,682,879 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	59,355,208 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; inferior ganglion of vagus nerve; ; internal globus pallidus; ; corpus callosum; ; pars reticulata; ; subthalamic nucleus; ; caput epididymis; ; Amygdala; ; putamen; ; middle frontal gyrus;
	Top expressed in
	ciliary body; ; iris; ; substantia nigra; ; Region I of hippocampus proper; ; tunica media of zone of aorta; ; deep cerebellar nuclei; ; ascending aorta; ; motor neuron; ; Amygdala; ; submandibular gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; cadherin binding;
Cellular component	cytoplasm; spindle pole; membrane; postsynaptic density; cell-cell contact zone; cell-cell junction; spindle; desmosome; cell junction; midbody; spindle midzone; perinuclear region of cytoplasm; cytoplasmic side of plasma membrane; mitotic spindle; cytoskeleton; cornified envelope; plasma membrane; nucleus;
Biological process	cell-cell signaling; positive regulation of cytokinesis; positive regulation of GTPase activity; regulation of cell adhesion; cell adhesion; cell-cell junction assembly; keratinization; cornification; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	8502
	227937
	ENSG00000144283
	ENSMUSG00000026991
	Q99569
	Q68FH0
NM_001005476; NM_001304969; NM_001304970; NM_001304971; NM_003628;
	NM_001377218; NM_001377219; NM_001377220; NM_001377221; NM_001377222; NM_001377223; NM_001377224; NM_001377225; NM_001377226
NM_026361; NM_175464; NM_001362990; NM_001362991; NM_001362992;
	NM_001362993; NM_001362994; NM_001362995; NM_001362996; NM_001362997; NM_001362998; NM_001362999
NP_001005476; NP_001291898; NP_001291899; NP_001291900; NP_003619;
	NP_001364147; NP_001364148; NP_001364149; NP_001364150; NP_001364151; NP_001364152; NP_001364153; NP_001364154; NP_001364155
NP_080637; NP_780673; NP_001349919; NP_001349920; NP_001349921;
	NP_001349922; NP_001349923; NP_001349924; NP_001349925; NP_001349926; NP_001349927; NP_001349928
	Wikidata
View/Edit Human	View/Edit Mouse

Plakophilin-4 is a protein that in humans is encoded by the PKP4 gene.