PLA2G2D

PLA2G2D
Identifiers
Aliases	PLA2G2D, PLA2IID, SPLASH, sPLA2-IID, sPLA2S, phospholipase A2 group IID
External IDs	OMIM: 605630; MGI: 1341796; HomoloGene: 7892; GeneCards: PLA2G2D; OMA:PLA2G2D - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	20,119,566 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	138,509,357 bp
RNA expression pattern
	Top expressed in
	lymph node; ; appendix; ; thymus; ; testicle; ; bone marrow cells; ; rectum; ; spleen; ; mucosa of transverse colon; ; gallbladder; ; pharynx;
	Top expressed in
	mesenteric lymph nodes; ; spleen; ; interventricular septum; ; thymus; ; sciatic nerve; ; subcutaneous adipose tissue; ; white adipose tissue; ; muscle of thigh; ; lip; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; phospholipase A2 activity; heparin binding; metal ion binding; heparan sulfate proteoglycan binding; hydrolase activity; phospholipid binding; calcium-dependent phospholipase A2 activity;
Cellular component	extracellular region;
Biological process	phosphatidic acid biosynthetic process; phosphatidylserine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; lipid metabolism; phosphatidylinositol acyl-chain remodeling; lipid catabolic process; negative regulation of T cell proliferation; phosphatidylglycerol acyl-chain remodeling; inflammatory response; negative regulation of T cell activation; phosphatidylcholine acyl-chain remodeling; phospholipid metabolic process; arachidonic acid secretion;
	Sources:Amigo / QuickGO
Orthologs
	26279
	18782
	ENSG00000117215
	ENSMUSG00000041202
	Q9UNK4
	Q9WVF6
	NM_012400; NM_001271814
	NM_011109; NM_001347230
	NP_001258743; NP_036532
	NP_001334159; NP_035239
	Wikidata
View/Edit Human	View/Edit Mouse

Group IID secretory phospholipase A₂ is an enzyme that in humans is encoded by the PLA2G2D gene.