Phospholipase A-2-activating protein

PLAA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K89, 2K8A, 2K8B, 2K8C, 3EBB
Identifiers
Aliases	PLAA, DOA1, PLA2P, PLAP, phospholipase A2 activating protein, NDMSBA
External IDs	OMIM: 603873; MGI: 104810; HomoloGene: 3138; GeneCards: PLAA; OMA:PLAA - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	26,947,242 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	94,491,481 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; secondary oocyte; ; stromal cell of endometrium; ; muscle of thigh; ; testicle; ; ganglionic eminence; ; monocyte; ; ventricular zone; ; gonad; ; Achilles tendon;
	Top expressed in
	tail of embryo; ; genital tubercle; ; zygote; ; secondary oocyte; ; epiblast; ; medial ganglionic eminence; ; Gonadal ridge; ; mandibular prominence; ; primitive streak; ; somite;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; phospholipase A2 activator activity; ubiquitin binding;
Cellular component	extracellular exosome; cytoplasm; nucleus; synapse; cell junction;
Biological process	phospholipid metabolic process; inflammatory response; signal transduction; ubiquitin recycling; proteasome-mediated ubiquitin-dependent protein catabolic process; macroautophagy; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; cellular response to lipopolysaccharide; negative regulation of protein K63-linked ubiquitination; positive regulation of synaptic vesicle recycling; positive regulation of dendrite extension; positive regulation of neuron migration; prostaglandin metabolic process; multicellular organism development; nervous system development; positive regulation of phospholipase A2 activity;
	Sources:Amigo / QuickGO
Orthologs
	9373
	18786
	ENSG00000137055
	ENSMUSG00000028577
	Q9Y263
	P27612
	NM_001031689; NM_004253; NM_001321546
	NM_172695
	NP_001026859; NP_001308475
	NP_766283
	Wikidata
View/Edit Human	View/Edit Mouse

Phospholipase A-2-activating protein is an enzyme that in humans is encoded by the PLAA gene.