Placenta-specific protein 1

PLAC1
Identifiers
Aliases	PLAC1, CT92, OOSP2L, placenta specific 1, OOSP2B, placenta enriched 1
External IDs	OMIM: 300296; MGI: 1926287; HomoloGene: 11039; GeneCards: PLAC1; OMA:PLAC1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	134,764,322 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	52,328,988 bp
RNA expression pattern
	Top expressed in
	placenta; ; oocyte; ; testicle; ; secondary oocyte; ; cartilage tissue; ; gonad; ; stromal cell of endometrium; ; right testis; ; left testis; ; metanephros;
	Top expressed in
	yolk sac; ; decidua; ; endocardial cushion; ; embryo; ; body wall; ; blastocyst; ; embryo; ; abdominal wall; ; primitive streak; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	molecular function;
Cellular component	extracellular region; cellular component;
Biological process	multicellular organism development; placenta development;
	Sources:Amigo / QuickGO
Orthologs
	10761
	56096
	ENSG00000170965
	ENSMUSG00000061082
	Q9HBJ0
	Q9JI83
	NM_021796; NM_001316887; NM_001316888; NM_001316889
	NM_019538; NM_001357802
	NP_001303816; NP_001303817; NP_001303818; NP_068568
	NP_062411; NP_001344731
	Wikidata
View/Edit Human	View/Edit Mouse

Placenta-specific protein 1 is a small (212 amino acid), secreted cell surface protein encoded on the X-chromosome by the PLAC1 gene. Since its discovery in 1999, PLAC1 has been found to play a role in placental development and maintenance, several gestational disorders including preeclampsia, fetal development and a large number of cancers.