PLCB2

PLCB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2FJU, 2ZKM
Identifiers
Aliases	PLCB2, PLC-beta-2, phospholipase C beta 2
External IDs	OMIM: 604114; MGI: 107465; HomoloGene: 20957; GeneCards: PLCB2; OMA:PLCB2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	40,307,935 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	118,558,919 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; spleen; ; blood; ; bone marrow cells; ; lymph node; ; appendix; ; upper lobe of left lung; ; right lung; ; C1 segment;
	Top expressed in
	granulocyte; ; thymus; ; female urethra; ; male urethra; ; lumbar subsegment of spinal cord; ; blood; ; spermatocyte; ; spleen; ; ascending aorta; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphoric diester hydrolase activity; phospholipase C activity; calcium ion binding; hydrolase activity; signal transducer activity; metal ion binding; phosphatidylinositol phospholipase C activity;
Cellular component	cytoplasm; cytosol;
Biological process	lipid catabolic process; sensory perception of bitter taste; phospholipid metabolic process; intracellular signal transduction; inositol phosphate metabolic process; activation of phospholipase C activity; signal transduction; lipid metabolism; Wnt signaling pathway, calcium modulating pathway; G protein-coupled receptor signaling pathway; inositol trisphosphate biosynthetic process; phosphatidylinositol-mediated signaling; release of sequestered calcium ion into cytosol;
	Sources:Amigo / QuickGO
Orthologs
	5330
	18796
	ENSG00000137841
	ENSMUSG00000040061
	Q00722
	A3KGF7
	NM_001284297; NM_001284298; NM_001284299; NM_004573
	NM_001290790; NM_177568
	NP_001271226; NP_001271227; NP_001271228; NP_004564
	NP_001277719; NP_808236
	Wikidata
View/Edit Human	View/Edit Mouse

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene.