Phospholipase D1

PLD1
Identifiers
Aliases	PLD1, phospholipase D1, CVDD
External IDs	OMIM: 602382; MGI: 109585; HomoloGene: 116234; GeneCards: PLD1; OMA:PLD1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	171,810,950 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	28,187,511 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; right adrenal cortex; ; mucosa of esophagus; ; duodenum; ; left adrenal gland; ; corpus callosum; ; left adrenal cortex; ; skin of abdomen; ; skin of leg; ; jejunal mucosa;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; crypt of lieberkuhn of small intestine; ; jejunum; ; ileum; ; left colon; ; vestibular membrane of cochlear duct; ; epithelium of lens; ; Paneth cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	phospholipase D activity; N-acylphosphatidylethanolamine-specific phospholipase D activity; protein binding; catalytic activity; phosphatidylinositol binding; hydrolase activity;
Cellular component	cytoplasm; late endosome membrane; Golgi membrane; endocytic vesicle; lysosomal membrane; apical plasma membrane; endoplasmic reticulum; perinuclear region of cytoplasm; endosome; endoplasmic reticulum membrane; membrane; Golgi apparatus; plasma membrane; specific granule membrane; tertiary granule membrane; cholinergic synapse;
Biological process	regulation of microvillus assembly; lipid metabolism; cell motility; small GTPase mediated signal transduction; lipid catabolic process; chemotaxis; Ras protein signal transduction; neutrophil degranulation; phosphatidic acid biosynthetic process; inositol lipid-mediated signaling; regulation of synaptic vesicle cycle;
	Sources:Amigo / QuickGO
Orthologs
	5337
	18805
	ENSG00000075651
	ENSMUSG00000027695
	Q13393
	Q9Z280
	NM_001130081; NM_002662
	NM_001164056; NM_008875; NM_001368667
	NP_001123553; NP_002653
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Phospholipase D₁ (PLD1) is an enzyme that in humans is encoded by the PLD1 gene, though analogues are found in plants, fungi, prokaryotes, and even viruses.