PLEK2

PLEK2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X1G
Identifiers
Aliases	PLEK2, pleckstrin 2
External IDs	OMIM: 608007; MGI: 1351466; HomoloGene: 8447; GeneCards: PLEK2; OMA:PLEK2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	67,412,167 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	78,953,738 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; mucosa of transverse colon; ; right adrenal cortex; ; gingival epithelium; ; left adrenal gland; ; left adrenal cortex; ; corpus epididymis; ; rectum; ; jejunal mucosa;
	Top expressed in
	Paneth cell; ; molar; ; fetal liver hematopoietic progenitor cell; ; lumbar spinal ganglion; ; gastric mucosa; ; mucous cell of stomach; ; epithelium of stomach; ; pyloric antrum; ; duodenum; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding;
Cellular component	cytoplasm; plasma membrane; cell projection; lamellipodium membrane; cytoskeleton; membrane;
Biological process	intracellular signal transduction; actin cytoskeleton organization; positive regulation of cell projection organization; actin cytoskeleton reorganization; positive regulation of plasma membrane bounded cell projection assembly;
	Sources:Amigo / QuickGO
Orthologs
	26499
	27260
	ENSG00000100558
	ENSMUSG00000021118
	Q9NYT0
	Q9WV52
	NM_016445
	NM_013738
	NP_057529
	NP_038766
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene. The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.