PLEKHA1

PLEKHA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EAZ
Identifiers
Aliases	PLEKHA1, TAPP1, pleckstrin homology domain containing A1
External IDs	OMIM: 607772; MGI: 2442213; HomoloGene: 11001; GeneCards: PLEKHA1; OMA:PLEKHA1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	122,442,602 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	130,515,042 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; sperm; ; Brodmann area 23; ; skin of hip; ; middle temporal gyrus; ; postcentral gyrus; ; gingival epithelium; ; synovial joint; ; endothelial cell; ; primary visual cortex;
	Top expressed in
	neural layer of retina; ; decidua; ; gastrula; ; ciliary body; ; olfactory bulb; ; iris; ; pineal gland; ; CA3 field; ; perirhinal cortex; ; sciatic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	PDZ domain binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding; lipid binding;
Cellular component	cytoplasm; membrane; nucleoplasm; ruffle membrane; extracellular exosome; nucleus; cytosol; plasma membrane;
Biological process	B cell receptor signaling pathway; roof of mouth development; negative regulation of protein kinase B signaling; luteinization; Leydig cell differentiation; estrogen metabolic process; androgen metabolic process; ruffle organization; multicellular organism growth; establishment of protein localization; skeletal system morphogenesis; post-embryonic development; female gonad development; spermatogenesis; phosphatidylinositol 3-kinase signaling; platelet-derived growth factor receptor signaling pathway; face morphogenesis; cellular response to hydrogen peroxide; phosphatidylinositol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	59338
	101476
	ENSG00000107679
	ENSMUSG00000040268
	Q9HB21
	Q8BUL6
	NM_001001974; NM_001195608; NM_021622; NM_001330178
NM_133942; NM_001346515; NM_001357696; NM_001382373; NM_001382374;
	NM_001382375; NM_001382376; NM_001382377; NM_001382378; NM_001382379
NP_001001974; NP_001182537; NP_001317107; NP_067635; NP_001364159;
	NP_001364160; NP_001364161; NP_001364163; NP_001364164; NP_001364166; NP_001364167; NP_001364169; NP_001364170; NP_001364171; NP_001364172; NP_001364173; NP_001364174; NP_001364175; NP_001364176; NP_001364177; NP_001364178; NP_001364179; NP_001364180; NP_001364181; NP_001364182; NP_001364183; NP_001364184; NP_001364185; NP_001364186; NP_001364187
NP_001333444; NP_598703; NP_001344625; NP_001369302; NP_001369303;
	NP_001369304; NP_001369305; NP_001369306; NP_001369307; NP_001369308
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin homology domain-containing family A member 1 is a protein that in humans is encoded by the PLEKHA1 gene.