PLEKHM1

PLEKHM1
Identifiers
Aliases	PLEKHM1, AP162, B2, OPTB6, pleckstrin homology and RUN domain containing M1, OPTA3
External IDs	OMIM: 611466; MGI: 2443207; HomoloGene: 8871; GeneCards: PLEKHM1; OMA:PLEKHM1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	45,490,749 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	103,303,513 bp
RNA expression pattern
	Top expressed in
	blood; ; bone marrow; ; bone marrow cells; ; skin of leg; ; vagina; ; minor salivary glands; ; right hemisphere of cerebellum; ; sural nerve; ; granulocyte; ; ectocervix;
	Top expressed in
	granulocyte; ; zygote; ; stroma of bone marrow; ; mesenteric lymph nodes; ; blood; ; transitional epithelium of urinary bladder; ; decidua; ; interventricular septum; ; right lung; ; otolith organ;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding;
Cellular component	lysosomal membrane; endosome membrane; lysosome; membrane; cytoplasm; endosome; nucleolus; intracellular membrane-bounded organelle;
Biological process	autophagy; protein transport; intracellular signal transduction; lysosome localization; positive regulation of bone resorption; positive regulation of ruffle assembly;
	Sources:Amigo / QuickGO
Orthologs
	9842
	353047
	ENSG00000277111; ENSG00000225190; ENSG00000276358
	ENSMUSG00000034247
	Q9Y4G2
	Q7TSI1
	NM_014798; NM_001352825
	NM_183034
	NP_055613; NP_001339754
	NP_898855
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin homology domain-containing family M member 1 also known as PLEKHM1 is a protein that in humans is encoded by the PLEKHM1 gene.