Perilipin-4

PLIN4
Identifiers
Aliases	PLIN4, KIAA1881, S3-12, perilipin 4
External IDs	OMIM: 613247; MGI: 1929709; HomoloGene: 69311; GeneCards: PLIN4; OMA:PLIN4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	4,518,486 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	56,416,803 bp
RNA expression pattern
	Top expressed in
	subcutaneous adipose tissue; ; muscle of thigh; ; apex of heart; ; gastrocnemius muscle; ; cardiac muscle tissue of right atrium; ; abdominal fat; ; myocardium of left ventricle; ; pericardium; ; Skeletal muscle tissue of rectus abdominis; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	white adipose tissue; ; subcutaneous adipose tissue; ; muscle of thigh; ; lactiferous gland; ; brown adipose tissue; ; tunica media of zone of aorta; ; tunica adventitia of aorta; ; ankle; ; intercostal muscle; ; medial head of gastrocnemius muscle;
	More reference expression data
	n/a
Orthologs
	729359
	57435
	ENSG00000167676
	ENSMUSG00000002831
	Q96Q06
	O88492
NM_001080400; NM_001367868; NM_001393888; NM_001393889; NM_001393890;
	NM_001393891
	NM_020568; NM_001372234
	NP_001354797
	NP_065593; NP_001359163
	Wikidata
View/Edit Human	View/Edit Mouse

Perilipin 4, also known as S3-12, is a protein that in humans is encoded by the PLIN4 gene on chromosome 19. It is highly expressed in white adipose tissue, with lower expression in heart, skeletal muscle, and brown adipose tissue. PLIN4 coats lipid droplets in adipocytes to protect them from lipases. The PLIN4 gene may be associated with insulin resistance and obesity risk.