PLK3

PLK3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4B6L
Identifiers
Aliases	PLK3, CNK, FNK, PRK, PLK-3, polo like kinase 3
External IDs	OMIM: 602913; MGI: 109604; HomoloGene: 20865; GeneCards: PLK3; OMA:PLK3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	44,805,990 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	116,991,160 bp
RNA expression pattern
	Top expressed in
	oocyte; ; gastric mucosa; ; ascending aorta; ; left uterine tube; ; gallbladder; ; upper lobe of left lung; ; skin of abdomen; ; Descending thoracic aorta; ; monocyte; ; secondary oocyte;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; CA3 field; ; granulocyte; ; lactiferous gland; ; choroid plexus of fourth ventricle; ; lip; ; left lobe of liver; ; decidua; ; esophagus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; p53 binding; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding;
Cellular component	cytoplasm; centrosome; Golgi apparatus; microtubule organizing center; soma; dendrite; nucleolus; Golgi stack; cytoskeleton; nucleus; nucleoplasm; spindle pole;
Biological process	positive regulation of intracellular protein transport; regulation of cytokinesis; regulation of cell division; protein kinase B signaling; phosphorylation; response to reactive oxygen species; mitotic cell cycle checkpoint signaling; mitotic G1/S transition checkpoint signaling; positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; cellular response to DNA damage stimulus; response to osmotic stress; protein phosphorylation; G2/M transition of mitotic cell cycle; cytoplasmic microtubule organization; endomitotic cell cycle; cell cycle; response to radiation; Golgi disassembly; apoptotic process; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of signal transduction by p53 class mediator; positive regulation of chaperone-mediated autophagy; G1/S transition of mitotic cell cycle; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	1263
	12795
	ENSG00000173846
	ENSMUSG00000028680
	Q9H4B4
	Q60806
	NM_004073
	NM_013807; NM_001313916
	NP_004064
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Polo-like kinase 3 (Drosophila), also known as PLK3, is an enzyme which in humans is encoded by the PLK3 gene.