PLXNB1

PLXNB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JPH, 2OS6, 2R2O, 2REX, 3HM6, 3OL2, 3SU8, 3SUA
Identifiers
Aliases	PLXNB1, PLEXIN-B1, PLXN5, SEP, plexin B1
External IDs	OMIM: 601053; MGI: 2154238; HomoloGene: 130508; GeneCards: PLXNB1; OMA:PLXNB1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	48,430,086 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,948,985 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; popliteal artery; ; tibial arteries; ; gastric mucosa; ; ventricular zone; ; skin of abdomen; ; skin of leg; ; right coronary artery;
	Top expressed in
	otic vesicle; ; neural layer of retina; ; lumbar subsegment of spinal cord; ; Rostral migratory stream; ; medullary collecting duct; ; ventricular zone; ; otolith organ; ; utricle; ; retinal pigment epithelium; ; lip;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	GTPase activating protein binding; semaphorin receptor activity; semaphorin receptor binding; protein binding; transmembrane signaling receptor activity; GTPase activator activity; signaling receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; semaphorin receptor complex; integral component of plasma membrane; extracellular region; intracellular anatomical structure;
Biological process	ossification involved in bone maturation; negative regulation of cell adhesion; neuron projection morphogenesis; intracellular signal transduction; positive regulation of axonogenesis; positive regulation of GTPase activity; regulation of cell shape; axon extension; negative regulation of osteoblast proliferation; positive regulation of phosphatidylinositol 3-kinase signaling; cell migration; regulation of cytoskeleton organization; semaphorin-plexin signaling pathway; signal transduction; semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis; regulation of GTPase activity; G protein-coupled receptor signaling pathway; regulation of cell migration; semaphorin-plexin signaling pathway involved in axon guidance; inhibitory synapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	5364
	235611
	ENSG00000164050
	ENSMUSG00000053646
	O43157
	Q8CJH3
	NM_001130082; NM_002673
	NM_172775
	NP_001123554; NP_002664
	NP_766363
	Wikidata
View/Edit Human	View/Edit Mouse

Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene.