POLDIP3

POLDIP3
Identifiers
Aliases	POLDIP3, PDIP46, SKAR, polymerase (DNA) delta interacting protein 3, DNA polymerase delta interacting protein 3, PDIP3
External IDs	OMIM: 611520; MGI: 1921076; HomoloGene: 13007; GeneCards: POLDIP3; OMA:POLDIP3 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	42,614,962 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,033,585 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; left ovary; ; oocyte; ; right ovary; ; granulocyte; ; right uterine tube; ; islet of Langerhans; ; cardia; ; body of uterus;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; motor neuron; ; condyle; ; Rostral migratory stream; ; fossa; ; medial ganglionic eminence; ; ascending aorta; ; aortic valve; ; vestibular membrane of cochlear duct;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; RNA binding; protein-containing complex binding;
Cellular component	exon-exon junction complex; transcription export complex; nucleus; nuclear speck; cytoplasm; cytosol; nucleoplasm; cytoplasmic ribonucleoprotein granule;
Biological process	poly(A)+ mRNA export from nucleus; mRNA transport; regulation of translation; positive regulation of translation; termination of RNA polymerase II transcription; mRNA 3'-end processing; RNA export from nucleus; mRNA export from nucleus; transport;
	Sources:Amigo / QuickGO
Orthologs
	84271
	73826
	ENSG00000100227
	ENSMUSG00000041815
	Q9BY77; Q8WUT1
	Q8BG81
	NM_001278657; NM_032311; NM_178136; NM_001363052
	NM_178627; NM_001347082
	NP_001265586; NP_115687; NP_835237; NP_001349981
	NP_001334011; NP_848742
	Wikidata
View/Edit Human	View/Edit Mouse

Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.