POLE2

POLE2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V6Z
Identifiers
Aliases	POLE2, DPE2, polymerase (DNA) epsilon 2, accessory subunit, DNA polymerase epsilon 2, accessory subunit
External IDs	OMIM: 602670; MGI: 1197514; HomoloGene: 2015; GeneCards: POLE2; OMA:POLE2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	49,688,422 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	69,274,969 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; ventricular zone; ; secondary oocyte; ; mucosa of transverse colon; ; rectum; ; ganglionic eminence; ; right uterine tube; ; mucosa of esophagus; ; ectocervix;
	Top expressed in
	tongue muscle; ; choroidal fissure; ; zygote; ; tail of embryo; ; spermatid; ; genital tubercle; ; blastocyst; ; embryo; ; morula; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; protein binding; DNA-directed DNA polymerase activity;
Cellular component	intracellular membrane-bounded organelle; nucleus; nucleoplasm; nuclear body; epsilon DNA polymerase complex;
Biological process	DNA repair; error-prone translesion synthesis; DNA replication; DNA-dependent DNA replication; G1/S transition of mitotic cell cycle; DNA replication initiation; telomere maintenance via semi-conservative replication;
	Sources:Amigo / QuickGO
Orthologs
	5427
	18974
	ENSG00000100479
	ENSMUSG00000020974
	P56282
	O54956
	NM_001197330; NM_001197331; NM_002692; NM_001348384; NM_001348385
	NM_011133
	NP_001184259; NP_001184260; NP_002683; NP_001335313; NP_001335314
	NP_035263
	Wikidata
View/Edit Human	View/Edit Mouse

DNA polymerase epsilon subunit 2 is an enzyme that in humans is encoded by the POLE2 gene.