DNA polymerase kappa

POLK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1T94, 2LSI, 2OH2, 2W7O, 2W7P, 3IN5, 3PZP, 4BA9, 4GK5, 4U6P, 4U7C
Identifiers
Aliases	POLK, DINB1, DINP, POLQ, polymerase (DNA) kappa, DNA polymerase kappa
External IDs	OMIM: 605650; MGI: 1349767; HomoloGene: 32140; GeneCards: POLK; OMA:POLK - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	75,601,144 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; superficial temporal artery; ; epithelium of colon; ; mucosa of paranasal sinus; ; skin of hip; ; trabecular bone; ; monocyte; ; islet of Langerhans; ; synovial membrane;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; damaged DNA binding; DNA-directed DNA polymerase activity; DNA binding; nucleotidyltransferase activity; metal ion binding; protein binding;
Cellular component	nucleoplasm; nucleus; nuclear body; site of DNA damage;
Biological process	nucleotide-excision repair, DNA gap filling; DNA replication; translesion synthesis; transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA incision; DNA biosynthetic process; nucleotide-excision repair, DNA incision, 5'-to lesion; DNA repair; cellular response to DNA damage stimulus; cellular response to UV; error-prone translesion synthesis; error-free translesion synthesis;
	Sources:Amigo / QuickGO
Orthologs
	51426
	27015
	ENSG00000122008
	ENSMUSG00000021668
	Q9UBT6
	Q9QUG2
	NM_016218; NM_001345921; NM_001345922
	NM_012048
	NP_001332850; NP_001332851; NP_057302; NP_057302.1
	NP_001334531; NP_001334532; NP_001334533; NP_001334535; NP_036178
	Wikidata
View/Edit Human	View/Edit Mouse

DNA polymerase kappa is a DNA polymerase that in humans is encoded by the POLK gene. It is involved in translesion synthesis.