DNA polymerase lambda

POLL
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NZP, 1RZT, 1XSL, 1XSN, 1XSP, 2BCQ, 2BCR, 2BCS, 2BCU, 2BCV, 2GWS, 2JW5, 2PFN, 2PFO, 2PFP, 2PFQ, 3C5F, 3C5G, 3HW8, 3HWT, 3HX0, 3MDA, 3MDC, 3MGH, 3MGI, 3PML, 3PMN, 3PNC, 3UPQ, 3UQ0, 3UQ2, 4FO6, 4K4G, 4K4H, 4K4I, 4XA5, 4XUS, 4X5V, 5CR0, 4XQ8, 5CJ7, 5DKW, 5CP2, 5DDY, 5DDM, 5CB1, 5CWR, 4XRH, 5CHG, 5CA7
Identifiers
Aliases	POLL, BETAN, POLKAPPA, polymerase (DNA) lambda, DNA polymerase lambda
External IDs	OMIM: 606343; MGI: 1889000; HomoloGene: 40863; GeneCards: POLL; OMA:POLL - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	101,588,270 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	45,548,970 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; body of pancreas; ; left testis; ; right testis; ; right lobe of thyroid gland; ; blood; ; body of stomach; ; granulocyte; ; apex of heart; ; anterior pituitary;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; muscle of thigh; ; secondary oocyte; ; primary oocyte; ; granulocyte; ; zygote; ; ventricular zone; ; medullary collecting duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; protein binding; metal ion binding; lyase activity; DNA-directed DNA polymerase activity; 5'-deoxyribose-5-phosphate lyase activity; DNA polymerase; DNA polymerase activity;
Cellular component	nucleus; nucleoplasm;
Biological process	DNA replication; nucleotide-excision repair; somatic hypermutation of immunoglobulin genes; cellular response to DNA damage stimulus; DNA repair; double-strand break repair via homologous recombination; base-excision repair, gap-filling; double-strand break repair via nonhomologous end joining; DNA biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	27343
	56626
	ENSG00000166169
	ENSMUSG00000025218
	Q9UGP5
	Q9QUG2; Q9QXE2
	NM_001174084; NM_001174085; NM_001308382; NM_013274
	NM_020032; NM_001330506; NM_001330507
	NP_001167555; NP_001167556; NP_001295311; NP_037406
NP_001334531; NP_001334532; NP_001334533; NP_001334535; NP_036178;
	NP_001317435; NP_001317436; NP_064416
	Wikidata
View/Edit Human	View/Edit Mouse

DNA polymerase lambda, also known as Pol λ, is an enzyme found in all eukaryotes. In humans, it is encoded by the POLL gene.