POLR1A

POLR1A
Identifiers
Aliases	POLR1A, A190, RPA1, RPA194, RPO1-4, RPO14, AFDCIN, polymerase (RNA) I subunit A, RNA polymerase I subunit A, RPA190
External IDs	OMIM: 616404; MGI: 1096397; HomoloGene: 7033; GeneCards: POLR1A; OMA:POLR1A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	86,106,155 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	71,961,919 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; tibialis anterior muscle; ; stromal cell of endometrium; ; gonad; ; testicle; ; islet of Langerhans; ; ventricular zone; ; gastrocnemius muscle; ; muscle of thigh; ; body of uterus;
	Top expressed in
	granulocyte; ; tail of embryo; ; epiblast; ; choroid plexus of fourth ventricle; ; primitive streak; ; genital tubercle; ; Epithelium of choroid plexus; ; yolk sac; ; spermatocyte; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; zinc ion binding; metal ion binding; DNA-directed 5'-3' RNA polymerase activity; protein binding; RNA polymerase I activity; chromatin binding;
Cellular component	nucleoplasm; RNA polymerase I complex; nucleus; nucleolus;
Biological process	termination of RNA polymerase I transcription; epigenetic maintenance of chromatin in transcription-competent conformation; transcription initiation from RNA polymerase I promoter; transcription, DNA-templated; negative regulation of protein localization to nucleolus; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
	25885
	20019
	ENSG00000068654
	ENSMUSG00000049553
	O95602
	O35134
	NM_015425
	NM_009088
	NP_056240
	NP_033114
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerase I subunit RPA1 is an enzyme that in humans is encoded by the POLR1A gene.