POLR2H

POLR2H
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F3I, 5FLM, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Identifiers
Aliases	POLR2H, RPABC3, RPB17, RPB8, polymerase (RNA) II subunit H, RNA polymerase II subunit H, RNA polymerase II, I and III subunit H
External IDs	OMIM: 606023; MGI: 2384309; HomoloGene: 4540; GeneCards: POLR2H; OMA:POLR2H - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	184,368,596 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	20,541,017 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; pancreatic ductal cell; ; right lobe of thyroid gland; ; right uterine tube; ; left lobe of thyroid gland; ; right adrenal gland; ; right adrenal cortex; ; left adrenal cortex; ; rectum; ; canal of the cervix;
	Top expressed in
	epiblast; ; embryo; ; morula; ; embryo; ; ventricular zone; ; neural tube; ; yolk sac; ; tail of embryo; ; ganglionic eminence; ; ileum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-directed 5'-3' RNA polymerase activity; DNA binding; RNA polymerase I activity; RNA polymerase II activity; RNA polymerase III activity; single-stranded DNA binding;
Cellular component	nucleolus; RNA polymerase II, core complex; nucleoplasm; cytosol; nucleus; RNA polymerase III complex; RNA polymerase I complex; protein-DNA complex;
Biological process	7-methylguanosine mRNA capping; transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; mRNA splicing, via spliceosome; epigenetic maintenance of chromatin in transcription-competent conformation; transcription-coupled nucleotide-excision repair; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase II promoter; transcription by RNA polymerase II; snRNA transcription by RNA polymerase II; fibroblast growth factor receptor signaling pathway; transcription by RNA polymerase III; RNA metabolic process; regulation of gene silencing by miRNA; transcription, DNA-templated; transcription elongation from RNA polymerase I promoter; positive regulation of type I interferon production; somatic stem cell population maintenance; positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologs
	5437
	245841
	ENSG00000163882
	ENSMUSG00000021018
	P52434
	Q923G2
NM_001278698; NM_001278699; NM_001278700; NM_001278714; NM_001278715;
	NM_006232; NM_001346879
	NM_145632; NM_001356423
NP_001265627; NP_001265628; NP_001265629; NP_001265643; NP_001265644;
	NP_001333808; NP_006223
	NP_663607; NP_001343352
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene.

This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.