PPIL4

PPIL4
Identifiers
Aliases	PPIL4, HDCME13P, peptidylprolyl isomerase like 4
External IDs	OMIM: 607609; MGI: 1914668; HomoloGene: 12126; GeneCards: PPIL4; OMA:PPIL4 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	149,546,043 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	7,698,899 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; epithelium of colon; ; testicle; ; left ovary; ; gonad; ; ventricular zone; ; right ovary; ; endometrium; ; islet of Langerhans; ; thymus;
	Top expressed in
	saccule; ; otic vesicle; ; otic placode; ; zygote; ; primitive streak; ; granulocyte; ; pituitary gland; ; seminal vesicula; ; neural layer of retina; ; blood;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	isomerase activity; nucleic acid binding; RNA binding; peptidyl-prolyl cis-trans isomerase activity;
Cellular component	nucleus; nucleoplasm; cytosol;
Biological process	protein peptidyl-prolyl isomerization; regulation of phosphorylation of RNA polymerase II C-terminal domain;
	Sources:Amigo / QuickGO
Orthologs
	85313
	67418
	ENSG00000131013
	ENSMUSG00000015757
	Q8WUA2
	Q9CXG3
	NM_139126
	NM_026141
	NP_624311
	NP_080417
	Wikidata
View/Edit Human	View/Edit Mouse

Peptidyl-prolyl cis-trans isomerase-like 4 is an enzyme that in humans is encoded by the PPIL4 gene.

This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions.