PPP2R5D

PPP2R5D
Identifiers
Aliases	PPP2R5D, B56D, MRD35, protein phosphatase 2 regulatory subunit B'delta, B56delta
External IDs	OMIM: 601646; MGI: 2388481; HomoloGene: 37661; GeneCards: PPP2R5D; OMA:PPP2R5D - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	43,012,342 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	47,016,037 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; prefrontal cortex; ; smooth muscle tissue; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; right frontal lobe; ; pancreatic ductal cell; ; gastrocnemius muscle; ; muscle of thigh;
	Top expressed in
	tail of embryo; ; yolk sac; ; genital tubercle; ; ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; epiblast; ; neural layer of retina; ; maxillary prominence; ; medial dorsal nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein serine/threonine phosphatase activity; protein binding; protein phosphatase regulator activity; phosphoprotein phosphatase activity; protein phosphatase activator activity;
Cellular component	cytoplasm; cytosol; protein phosphatase type 2A complex; nucleoplasm; nucleus;
Biological process	nervous system development; signal transduction; positive regulation of protein dephosphorylation; protein dephosphorylation; regulation of phosphoprotein phosphatase activity; negative regulation of peptidyl-threonine phosphorylation; regulation of protein autophosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	5528
	21770
	ENSG00000112640
	ENSMUSG00000059409
	Q14738
	n/a
	NM_180977; NM_001270476; NM_006245; NM_180976
	NM_009358; NM_001357684
	NP_001257405; NP_006236; NP_851307; NP_851308
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations in PPP2R5D cause Jordan's syndrome.