Peroxiredoxin 1

PRDX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2RII, 3HY2, 4XCS
Identifiers
Aliases	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1
External IDs	OMIM: 176763; MGI: 99523; HomoloGene: 99789; GeneCards: PRDX1; OMA:PRDX1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	45,542,732 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	116,558,019 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; nasal epithelium; ; olfactory zone of nasal mucosa; ; palpebral conjunctiva; ; C1 segment; ; mucosa of esophagus; ; ganglionic eminence; ; gums; ; gingival epithelium;
	Top expressed in
	vas deferens; ; primitive streak; ; endothelial cell of lymphatic vessel; ; right kidney; ; Gonadal ridge; ; efferent ductule; ; lobe of prostate; ; stroma of bone marrow; ; iris; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	antioxidant activity; protein binding; peroxiredoxin activity; identical protein binding; oxidoreductase activity; thioredoxin peroxidase activity; peroxidase activity; RNA binding; cadherin binding;
Cellular component	cytoplasm; cytosol; melanosome; myelin sheath; mitochondrion; extracellular exosome; nucleus; extracellular matrix; extracellular space;
Biological process	skeletal system development; removal of superoxide radicals; response to oxidative stress; retina homeostasis; erythrocyte homeostasis; hydrogen peroxide catabolic process; cell population proliferation; regulation of stress-activated MAPK cascade; natural killer cell mediated cytotoxicity; cell redox homeostasis; natural killer cell activation; response to reactive oxygen species; cellular response to oxidative stress; regulation of NIK/NF-kappaB signaling; leukocyte activation;
	Sources:Amigo / QuickGO
Orthologs
	5052
	18477
	ENSG00000117450
	ENSMUSG00000028691
	Q06830
	P35700
	NM_181697; NM_001202431; NM_002574; NM_181696
	NM_011034
	NP_001189360; NP_002565; NP_859047; NP_859048
	NP_035164
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxiredoxin-1 is a protein that in humans is encoded by the PRDX1 gene.