PRKAR1A

PRKAR1A
Identifiers
Aliases	PRKAR1A, ACRDYS1, ADOHR, CAR, CNC, CNC1, PKR1, PPNAD1, PRKAR1, TSE1, protein kinase cAMP-dependent type I regulatory subunit alpha
External IDs	OMIM: 188830; MGI: 104878; HomoloGene: 37664; GeneCards: PRKAR1A; OMA:PRKAR1A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	68,551,319 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	109,560,482 bp
RNA expression pattern
	Top expressed in
	mucosa of paranasal sinus; ; germinal epithelium; ; lateral nuclear group of thalamus; ; bronchial epithelial cell; ; epithelium of nasopharynx; ; Epithelium of choroid plexus; ; superficial temporal artery; ; pars compacta; ; pars reticulata; ; caput epididymis;
	Top expressed in
	arcuate nucleus; ; ventral tegmental area; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; median eminence; ; cingulate gyrus; ; ventromedial nucleus; ; mammillary body; ; subiculum; ; anterior amygdaloid area;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein kinase A catalytic subunit binding; cAMP binding; protein binding; cAMP-dependent protein kinase regulator activity; cAMP-dependent protein kinase inhibitor activity; ubiquitin protein ligase binding; protein domain specific binding; 3',5'-cyclic-GMP phosphodiesterase activity; kinase activity;
Cellular component	cytoplasm; cytosol; membrane; plasma membrane raft; neuromuscular junction; plasma membrane; ciliary base; nucleotide-activated protein kinase complex; immunological synapse; cAMP-dependent protein kinase complex; axoneme; protein-containing complex; synapse; glutamatergic synapse;
Biological process	regulation of protein phosphorylation; activation of protein kinase A activity; intracellular signal transduction; negative regulation of protein kinase activity; regulation of transcription by RNA polymerase II; cellular response to glucagon stimulus; mesoderm formation; blood coagulation; female meiotic nuclear division; negative regulation of meiotic nuclear division; cardiac muscle cell proliferation; negative regulation of cAMP-dependent protein kinase activity; negative regulation of activated T cell proliferation; heart development; renal water homeostasis; regulation of protein kinase activity; sarcomere organization; cGMP-mediated signaling; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	5573
	19084
	ENSG00000108946
	ENSMUSG00000020612
	P10644
	Q9DBC7
NM_001276289; NM_001276290; NM_001278433; NM_002734; NM_212471;
	NM_212472; NM_001369389; NM_001369390
NM_021880; NM_001313973; NM_001313974; NM_001313975; NM_001313976;
	NM_001362677; NM_001373912; NM_001373913
NP_001263218; NP_001263219; NP_001265362; NP_002725; NP_997636;
	NP_997637; NP_001356318; NP_001356319; NP_001263218.1; NP_001265362.1; NP_002725.1; NP_997636.1; NP_997637.1
NP_001300902; NP_001300903; NP_001300904; NP_001300905; NP_068680;
	NP_001349606; NP_001360841; NP_001360842
	Wikidata
View/Edit Human	View/Edit Mouse

cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene.