PRKAR1B

PRKAR1B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4DIN, 4F9K
Identifiers
Aliases	PRKAR1B, PRKAR1, protein kinase cAMP-dependent type I regulatory subunit beta, MASNS
External IDs	OMIM: 176911; MGI: 97759; HomoloGene: 37665; GeneCards: PRKAR1B; OMA:PRKAR1B - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	727,650 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	139,135,756 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; frontal pole; ; Brodmann area 9; ; Amygdala; ; nucleus accumbens; ; right hemisphere of cerebellum; ; Hypothalamus;
	Top expressed in
	substantia nigra; ; motor neuron; ; dorsal tegmental nucleus; ; ventromedial nucleus; ; dorsomedial hypothalamic nucleus; ; prefrontal cortex; ; subiculum; ; pontine nuclei; ; anterior amygdaloid area; ; ventral tegmental area;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; protein kinase A catalytic subunit binding; cAMP binding; cAMP-dependent protein kinase regulator activity; cAMP-dependent protein kinase inhibitor activity; protein binding; 3',5'-cyclic-GMP phosphodiesterase activity;
Cellular component	cytosol; membrane; plasma membrane; ciliary base; cAMP-dependent protein kinase complex; synapse; Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; glutamatergic synapse;
Biological process	regulation of protein phosphorylation; activation of protein kinase A activity; cellular response to glucagon stimulus; blood coagulation; negative regulation of cAMP-dependent protein kinase activity; protein phosphorylation; renal water homeostasis; learning or memory; modulation of chemical synaptic transmission; regulation of synaptic vesicle cycle; cGMP-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	5575
	19085
	ENSG00000188191
	ENSMUSG00000025855
	P31321
	P12849
NM_001164758; NM_001164759; NM_001164760; NM_001164761; NM_001164762;
	NM_002735
NM_001253890; NM_008923; NM_001359097; NM_001359098; NM_001359099;
	NM_001359100; NM_001359101
NP_001158230; NP_001158231; NP_001158232; NP_001158233; NP_001158234;
	NP_002726
NP_001240819; NP_032949; NP_001346026; NP_001346027; NP_001346028;
	NP_001346029; NP_001346030
	Wikidata
View/Edit Human	View/Edit Mouse

cAMP-dependent protein kinase type I-beta regulatory subunit is an enzyme that in humans is encoded by the PRKAR1B gene.