PRKAR2B

PRKAR2B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3TNP, 3TNQ, 4WBB, 4X6Q
Identifiers
Aliases	PRKAR2B, PRKAR2, RII-BETA, protein kinase cAMP-dependent type II regulatory subunit beta
External IDs	OMIM: 176912; MGI: 97760; HomoloGene: 37666; GeneCards: PRKAR2B; OMA:PRKAR2B - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,161,811 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	32,111,295 bp
RNA expression pattern
	Top expressed in
	monocyte; ; gastric mucosa; ; subcutaneous adipose tissue; ; superior frontal gyrus; ; right adrenal cortex; ; left adrenal cortex; ; ganglionic eminence; ; primary visual cortex; ; prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	brown adipose tissue; ; pineal gland; ; subcutaneous adipose tissue; ; olfactory tubercle; ; white adipose tissue; ; cumulus cell; ; blood; ; lateral septal nucleus; ; mammary gland; ; Gonadal ridge;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein domain specific binding; protein kinase A catalytic subunit binding; cAMP binding; cAMP-dependent protein kinase regulator activity; cAMP-dependent protein kinase inhibitor activity; protein kinase binding; ubiquitin protein ligase binding; protein binding; 3',5'-cyclic-GMP phosphodiesterase activity; kinase activity;
Cellular component	cytoplasm; cytosol; centrosome; membrane; plasma membrane; dendritic spine; ciliary base; dendritic shaft; soma; dendrite; perinuclear region of cytoplasm; mitochondrial inner membrane; membrane raft; cAMP-dependent protein kinase complex; extracellular exosome; postsynapse; glutamatergic synapse;
Biological process	regulation of protein phosphorylation; activation of protein kinase A activity; intracellular signal transduction; response to antipsychotic drug; cellular response to glucagon stimulus; blood coagulation; learning; negative regulation of cAMP-dependent protein kinase activity; fatty acid metabolic process; G2/M transition of mitotic cell cycle; response to clozapine; renal water homeostasis; regulation of protein kinase activity; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; cGMP-mediated signaling; modulation of chemical synaptic transmission; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	5577
	19088
	ENSG00000005249; ENSG00000284096
	ENSMUSG00000002997
	P31323
	P31324
	NM_002736
	NM_011158; NM_001364407; NM_001364408
	NP_002727; NP_002727.2
	NP_035288; NP_001351336; NP_001351337
	Wikidata
View/Edit Human	View/Edit Mouse

cAMP-dependent protein kinase type II-beta regulatory subunit is an enzyme that in humans is encoded by the PRKAR2B gene.