PRKCD

PRKCD
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YUU, 1YRK
Identifiers
Aliases	PRKCD, ALPS3, CVID9, MAY1, PKCD, nPKC-delta, protein kinase C delta
External IDs	OMIM: 176977; MGI: 97598; HomoloGene: 55963; GeneCards: PRKCD; OMA:PRKCD - orthologs
EC number	2.7.10.2
Gene location (Human)
Chr.	Chromosome 3 (human)
End	53,192,717 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	30,348,167 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; right adrenal cortex; ; right uterine tube; ; mucosa of transverse colon; ; left adrenal gland; ; left adrenal cortex; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; rectum;
	Top expressed in
	lateral geniculate nucleus; ; granulocyte; ; medial dorsal nucleus; ; medial geniculate nucleus; ; lateral septal nucleus; ; pyloric antrum; ; seminiferous tubule; ; epithelium of stomach; ; large intestine; ; colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	kinase activity; ATP binding; protein kinase activity; non-membrane spanning protein tyrosine kinase activity; metal ion binding; kinase binding; enzyme binding; insulin receptor substrate binding; transferase activity; protein binding; calcium-independent protein kinase C activity; protein kinase binding; nucleotide binding; enzyme activator activity; protein serine/threonine kinase activity; protein kinase C activity;
Cellular component	cytoplasm; cytosol; membrane; cell-cell junction; perinuclear region of cytoplasm; nucleus; nuclear matrix; endoplasmic reticulum; extracellular exosome; plasma membrane; nucleoplasm; extracellular region; azurophil granule lumen;
Biological process	intrinsic apoptotic signaling pathway in response to oxidative stress; termination of signal transduction; interferon-gamma-mediated signaling pathway; negative regulation of protein binding; positive regulation of endodeoxyribonuclease activity; platelet activation; protein phosphorylation; cellular senescence; negative regulation of insulin receptor signaling pathway; positive regulation of sphingomyelin catabolic process; cell chemotaxis; cell cycle; negative regulation of inflammatory response; positive regulation of protein dephosphorylation; Fc-gamma receptor signaling pathway involved in phagocytosis; positive regulation of apoptotic signaling pathway; stimulatory C-type lectin receptor signaling pathway; cellular response to hydroperoxide; negative regulation of peptidyl-tyrosine phosphorylation; defense response to bacterium; negative regulation of MAP kinase activity; positive regulation of response to DNA damage stimulus; positive regulation of protein import into nucleus; interleukin-10 production; regulation of actin cytoskeleton organization; negative regulation of actin filament polymerization; regulation of mRNA stability; phosphorylation; protein stabilization; regulation of signaling receptor activity; negative regulation of filopodium assembly; cellular response to angiotensin; interleukin-12 production; peptidyl-threonine phosphorylation; positive regulation of ceramide biosynthetic process; neutrophil activation; intracellular signal transduction; negative regulation of glial cell apoptotic process; negative regulation of platelet aggregation; positive regulation of phospholipid scramblase activity; B cell proliferation; immunoglobulin mediated immune response; positive regulation of glucosylceramide catabolic process; peptidyl-tyrosine phosphorylation; positive regulation of superoxide anion generation; activation of protein kinase activity; signal transduction; cellular response to hydrogen peroxide; peptidyl-serine phosphorylation; apoptotic process; neutrophil degranulation; execution phase of apoptosis;
	Sources:Amigo / QuickGO
Orthologs
	5580
	18753
	ENSG00000163932
	ENSMUSG00000021948
	Q05655
	P28867
NM_006254; NM_212539; NM_001316327; NM_001354676; NM_001354678;
	NM_001354679; NM_001354680
	NM_011103; NM_001310682
NP_001303256; NP_006245; NP_997704; NP_001341605; NP_001341607;
	NP_001341608; NP_001341609
	NP_001297611; NP_035233
	Wikidata
View/Edit Human	View/Edit Mouse

Protein kinase C delta type (or PKC-δ) is an enzyme that in humans is encoded by the PRKCD gene.