Prolactin-releasing peptide

PRLH
Identifiers
Aliases	PRLH, PRH, PRRP, prolactin releasing hormone
External IDs	OMIM: 602663; MGI: 3644668; HomoloGene: 9291; GeneCards: PRLH; OMA:PRLH - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	237,567,175 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	90,881,749 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; tendon of biceps brachii; ; right auricle of heart; ; skin of thigh; ; right uterine tube; ; optic nerve; ; face; ; sensory organ; ; lower respiratory tract; ; mucosa of nose;
	Top expressed in
	blastocyst; ; granulocyte; ; bone marrow; ; cerebellar cortex; ; colon; ; Hypothalamus; ; duodenum; ; human kidney; ; proximal tubule; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	neuropeptide hormone activity; prolactin-releasing peptide receptor binding; hormone activity;
Cellular component	cytoplasm; extracellular region;
Biological process	tissue homeostasis; reduction of food intake in response to dietary excess; energy reserve metabolic process; lipid metabolism; G protein-coupled receptor signaling pathway; response to glucose; response to insulin; regulation of multicellular organism growth; fat cell differentiation; autonomic nervous system development; response to dietary excess; response to peptide hormone; eating behavior; feeding behavior; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	51052
	623503
	ENSG00000071677
	ENSMUSG00000090550
	P81277
	G3UWC3
	NM_015893
	NM_001101647
	NP_056977
	NP_001095117
	Wikidata
View/Edit Human	View/Edit Mouse

Prolactin-releasing peptide (PrRP) is a peptide hormone that in humans is encoded by the PRLH gene. PrRP stimulates prolactin (PRL) release and regulates the expression of prolactin through binding to the prolactin-releasing peptide receptor (GPR10).