PRRX1

PRRX1
Identifiers
Aliases	PRRX1, AGOTC, PHOX1, PMX1, PRX-1, PRX1, paired related homeobox 1
External IDs	OMIM: 167420; MGI: 97712; HomoloGene: 7896; GeneCards: PRRX1; OMA:PRRX1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	170,739,421 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	163,141,279 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; urethra; ; tendon of biceps brachii; ; saphenous vein; ; parietal pleura; ; synovial joint; ; vena cava; ; pericardium; ; skin of hip; ; seminal vesicula;
	Top expressed in
	calvaria; ; maxillary prominence; ; dermis; ; genital tubercle; ; foot; ; ankle; ; mandibular prominence; ; stroma of bone marrow; ; body of femur; ; skin of external ear;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; transcription coactivator activity; DNA binding; HMG box domain binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytosol;
Biological process	embryonic skeletal system morphogenesis; roof of mouth development; regulation of transcription, DNA-templated; neuron fate determination; positive regulation of smoothened signaling pathway; regulation of neuron projection regeneration; negative regulation of transcription by RNA polymerase II; neuronal stem cell population maintenance; multicellular organism development; cartilage development; positive regulation of mesenchymal cell proliferation; embryonic limb morphogenesis; inner ear morphogenesis; artery morphogenesis; middle ear morphogenesis; embryonic cranial skeleton morphogenesis; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	5396
	18933
	ENSG00000116132
	ENSMUSG00000026586
	P54821
	P63013
	NM_006902; NM_022716
	NM_001025570; NM_011127; NM_175686
	NP_008833; NP_073207
	NP_001020741; NP_035257; NP_783617
	Wikidata
View/Edit Human	View/Edit Mouse

Paired related homeobox 1 is a protein that in humans is encoded by the PRRX1 gene.