PRSS23

PRSS23
Identifiers
Aliases	PRSS23, SIG13, SPUVE, ZSIG13, protease, serine 23, serine protease 23
External IDs	OMIM: 618376; MGI: 1923703; HomoloGene: 5191; GeneCards: PRSS23; OMA:PRSS23 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	86,952,910 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	89,176,395 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; cartilage tissue; ; right coronary artery; ; saphenous vein; ; decidua; ; urethra; ; epithelium of bronchus; ; bronchial epithelial cell;
	Top expressed in
	endothelial cell of lymphatic vessel; ; cervix; ; stroma of bone marrow; ; conjunctival fornix; ; seminal vesicula; ; tunica media of zone of aorta; ; cornea; ; vestibular sensory epithelium; ; calvaria; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity; hydrolase activity;
Cellular component	extracellular region; extracellular exosome; nucleus; extracellular space; endoplasmic reticulum lumen;
Biological process	proteolysis; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	11098
	76453
	ENSG00000150687
	ENSMUSG00000039405
	O95084
	Q9D6X6
	NM_001293178; NM_001293179; NM_001293180; NM_007173
NM_029614; NM_001360752; NM_001360753; NM_001360754; NM_001360755;
	NM_001360756; NM_001384148; NM_001384151
	NP_001280108; NP_001280109; NP_009104
NP_083890; NP_001347681; NP_001347682; NP_001347683; NP_001347684;
	NP_001347685; NP_001371077; NP_001371080
	Wikidata
View/Edit Human	View/Edit Mouse

Serine protease 23 is an enzyme that in humans is encoded by the PRSS23 gene.

This gene encodes a member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels after ovulation was induced. This gene seems to be highly conserved in vertebrates and may be an important ovarian protease.