PSMD11

PSMD11
Identifiers
Aliases	PSMD11, Rpn6, S9, p44.5, proteasome 26S subunit, non-ATPase 11
External IDs	OMIM: 604449; MGI: 1916327; HomoloGene: 2108; GeneCards: PSMD11; OMA:PSMD11 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	32,483,319 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	80,364,074 bp
RNA expression pattern
	Top expressed in
	oocyte; ; gastrocnemius muscle; ; islet of Langerhans; ; cartilage tissue; ; tibialis anterior muscle; ; nipple; ; secondary oocyte; ; body of tongue; ; skin of thigh; ; mucosa of pharynx;
	Top expressed in
	morula; ; Ileal epithelium; ; blastocyst; ; ankle; ; external carotid artery; ; internal carotid artery; ; digastric muscle; ; embryo; ; muscle of thigh; ; extraocular muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; structural molecule activity;
Cellular component	cytoplasm; cytosol; membrane; proteasome accessory complex; proteasome regulatory particle; nucleoplasm; proteasome complex; extracellular exosome; nucleus; extracellular region; proteasome regulatory particle, lid subcomplex; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; ubiquitin-dependent protein catabolic process; regulation of mRNA stability; positive regulation of canonical Wnt signaling pathway; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; stem cell differentiation; MAPK cascade; Fc-epsilon receptor signaling pathway; NIK/NF-kappaB signaling; anaphase-promoting complex-dependent catabolic process; T cell receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; Wnt signaling pathway, planar cell polarity pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of G2/M transition of mitotic cell cycle; protein deubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; neutrophil degranulation; transmembrane transport; regulation of transcription from RNA polymerase II promoter in response to hypoxia; post-translational protein modification; proteasome assembly; regulation of hematopoietic stem cell differentiation; interleukin-1-mediated signaling pathway; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	5717
	69077
	ENSG00000108671
	ENSMUSG00000017428
	O00231
	Q8BG32
	NM_002815; NM_001270482
	NM_178616
	NP_001257411; NP_002806
	NP_848731
	Wikidata
View/Edit Human	View/Edit Mouse

26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene.