PSMD3

PSMD3
Identifiers
Aliases	PSMD3, P58, RPN3, S3, TSTA2, proteasome 26S subunit, non-ATPase 3
External IDs	OMIM: 617676; MGI: 98858; HomoloGene: 2102; GeneCards: PSMD3; OMA:PSMD3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	39,997,959 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	98,586,805 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; skin of leg; ; mucosa of transverse colon; ; skin of abdomen; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; ganglionic eminence; ; body of uterus; ; gastric mucosa;
	Top expressed in
	muscle of thigh; ; lip; ; yolk sac; ; right kidney; ; ventricular zone; ; proximal tubule; ; epiblast; ; superior frontal gyrus; ; primary visual cortex; ; perirhinal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme regulator activity; protein binding;
Cellular component	cytosol; membrane; proteasome accessory complex; proteasome regulatory particle; proteasome regulatory particle, lid subcomplex; proteasome complex; extracellular exosome; nucleus; extracellular region; nucleoplasm; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; ubiquitin-dependent protein catabolic process; regulation of mRNA stability; positive regulation of canonical Wnt signaling pathway; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; MAPK cascade; Fc-epsilon receptor signaling pathway; NIK/NF-kappaB signaling; regulation of protein catabolic process; anaphase-promoting complex-dependent catabolic process; T cell receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; Wnt signaling pathway, planar cell polarity pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of G2/M transition of mitotic cell cycle; protein deubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; neutrophil degranulation; transmembrane transport; regulation of transcription from RNA polymerase II promoter in response to hypoxia; post-translational protein modification; regulation of hematopoietic stem cell differentiation; regulation of catalytic activity; interleukin-1-mediated signaling pathway; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	5709
	22123
	ENSG00000108344
	ENSMUSG00000017221
	O43242
	P14685
	NM_002809
	NM_009439
	NP_002800
	NP_033465
	Wikidata
View/Edit Human	View/Edit Mouse

26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene.