PSMD5

PSMD5
Identifiers
Aliases	PSMD5, S5B, proteasome 26S subunit, non-ATPase 5
External IDs	OMIM: 604452; MGI: 1914248; HomoloGene: 37999; GeneCards: PSMD5; OMA:PSMD5 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	120,842,951 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	34,764,980 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; tibia; ; epithelium of lactiferous gland; ; lactiferous duct; ; islet of Langerhans; ; Achilles tendon; ; secondary oocyte; ; periodontal fiber; ; lower lobe of lung; ; gums;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; secondary oocyte; ; primary oocyte; ; right kidney; ; medial ganglionic eminence; ; endothelial cell of lymphatic vessel; ; neural tube; ; dentate gyrus of hippocampal formation granule cell; ; proximal tubule; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytosol; proteasome regulatory particle, base subcomplex; proteasome accessory complex; nucleoplasm; proteasome complex;
Biological process	proteasome regulatory particle assembly; proteasome assembly; protein deubiquitination; post-translational protein modification; MAPK cascade; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of cellular amino acid metabolic process; negative regulation of G2/M transition of mitotic cell cycle; anaphase-promoting complex-dependent catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; tumor necrosis factor-mediated signaling pathway; NIK/NF-kappaB signaling; Fc-epsilon receptor signaling pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; regulation of mRNA stability; T cell receptor signaling pathway; transmembrane transport; Wnt signaling pathway, planar cell polarity pathway; regulation of transcription from RNA polymerase II promoter in response to hypoxia; interleukin-1-mediated signaling pathway; negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; regulation of mitotic cell cycle phase transition; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	5711
	66998
	ENSG00000095261
	ENSMUSG00000026869
	Q16401
	Q8BJY1
	NM_001270427; NM_005047
	NM_080554; NM_001355544
	NP_001257356; NP_005038
	NP_542121; NP_001342473
	Wikidata
View/Edit Human	View/Edit Mouse

26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.