PSMD6

PSMD6
Identifiers
Aliases	PSMD6, Rpn7, S10, SGA-113M, p42A, p44S10, proteasome 26S subunit, non-ATPase 6
External IDs	OMIM: 617857; MGI: 1913663; HomoloGene: 7157; GeneCards: PSMD6; OMA:PSMD6 - orthologs
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	8,357,589 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; sperm; ; tibialis anterior muscle; ; gastrocnemius muscle; ; islet of Langerhans; ; deltoid muscle; ; Achilles tendon; ; right adrenal gland; ; triceps brachii muscle; ; left adrenal gland;
	Top expressed in
	otic placode; ; saccule; ; abdominal wall; ; external carotid artery; ; intercostal muscle; ; internal carotid artery; ; medial ganglionic eminence; ; somite; ; otic vesicle; ; vas deferens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATPase activity; protein binding; enzyme regulator activity;
Cellular component	cytosol; proteasome accessory complex; proteasome regulatory particle; nucleoplasm; proteasome complex; extracellular region; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	proteolysis; protein deubiquitination; neutrophil degranulation; post-translational protein modification; regulation of catalytic activity; proteasome-mediated ubiquitin-dependent protein catabolic process; MAPK cascade; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of cellular amino acid metabolic process; negative regulation of G2/M transition of mitotic cell cycle; anaphase-promoting complex-dependent catabolic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; tumor necrosis factor-mediated signaling pathway; NIK/NF-kappaB signaling; Fc-epsilon receptor signaling pathway; regulation of mRNA stability; T cell receptor signaling pathway; transmembrane transport; Wnt signaling pathway, planar cell polarity pathway; regulation of transcription from RNA polymerase II promoter in response to hypoxia; interleukin-1-mediated signaling pathway; negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; regulation of mitotic cell cycle phase transition; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	9861
	66413
	n/a
	ENSMUSG00000021737
	Q15008
	Q99JI4
	NM_001271779; NM_001271780; NM_001271781; NM_014814
	NM_025550
	NP_001258708; NP_001258709; NP_001258710; NP_055629
	NP_079826
	Wikidata
View/Edit Human	View/Edit Mouse

26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene.