PSME2

PSME2
Identifiers
Aliases	PSME2, PA28B, PA28beta, REGbeta, proteasome activator subunit 2
External IDs	OMIM: 602161; MGI: 1096365; HomoloGene: 86889; GeneCards: PSME2; OMA:PSME2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,147,570 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,828,570 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; duodenum; ; appendix; ; spleen; ; right adrenal cortex; ; mucosa of transverse colon; ; lymph node; ; pituitary gland; ; left adrenal gland; ; left adrenal cortex;
	Top expressed in
	jejunum; ; duodenum; ; ileum; ; colon; ; adrenal gland; ; ovary; ; uterus; ; epiblast; ; spleen; ; white adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	endopeptidase activator activity; protein binding; identical protein binding;
Cellular component	cytoplasm; cytosol; membrane; proteasome activator complex; nucleoplasm; proteasome complex; extracellular exosome;
Biological process	positive regulation of endopeptidase activity; regulation of proteasomal protein catabolic process; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of mRNA stability; positive regulation of canonical Wnt signaling pathway; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; MAPK cascade; Fc-epsilon receptor signaling pathway; regulation of G1/S transition of mitotic cell cycle; NIK/NF-kappaB signaling; anaphase-promoting complex-dependent catabolic process; T cell receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; Wnt signaling pathway, planar cell polarity pathway; negative regulation of G2/M transition of mitotic cell cycle; protein deubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; transmembrane transport; regulation of transcription from RNA polymerase II promoter in response to hypoxia; post-translational protein modification; interleukin-12-mediated signaling pathway; regulation of hematopoietic stem cell differentiation; interleukin-1-mediated signaling pathway; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	5721
	19188
	ENSG00000100911; ENSG00000284889
	ENSMUSG00000079197
	Q9UL46
	P97372
	NM_002818
	NM_001029855; NM_011190
	NP_002809
	NP_001268401
	Wikidata
View/Edit Human	View/Edit Mouse

Proteasome activator complex subunit 2 is a protein that in humans is encoded by the PSME2 gene.