PSME4

PSME4
Identifiers
Aliases	PSME4, PA200, proteasome activator subunit 4
External IDs	OMIM: 607705; MGI: 2143994; HomoloGene: 113742; GeneCards: PSME4; OMA:PSME4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	53,970,993 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	30,830,361 bp
RNA expression pattern
	Top expressed in
	sperm; ; glutes; ; gastrocnemius muscle; ; left testis; ; biceps brachii; ; right testis; ; Skeletal muscle tissue of biceps brachii; ; deltoid muscle; ; triceps brachii muscle; ; vastus lateralis muscle;
	Top expressed in
	temporal muscle; ; triceps brachii muscle; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; digastric muscle; ; myocardium of ventricle; ; gastrocnemius muscle; ; spermatid; ; medial head of gastrocnemius muscle; ; cardiac muscles;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; peptidase activator activity; lysine-acetylated histone binding; proteasome binding;
Cellular component	cytoplasm; nuclear speck; proteasome complex; nucleus; nucleoplasm; cytosol; proteasome core complex; spermatoproteasome complex;
Biological process	cell differentiation; regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; regulation of mRNA stability; positive regulation of canonical Wnt signaling pathway; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; MAPK cascade; cellular response to DNA damage stimulus; positive regulation of peptidase activity; multicellular organism development; Fc-epsilon receptor signaling pathway; NIK/NF-kappaB signaling; spermatogenesis; anaphase-promoting complex-dependent catabolic process; T cell receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; Wnt signaling pathway, planar cell polarity pathway; proteasomal ubiquitin-independent protein catabolic process; negative regulation of G2/M transition of mitotic cell cycle; protein deubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; transmembrane transport; regulation of transcription from RNA polymerase II promoter in response to hypoxia; post-translational protein modification; regulation of hematopoietic stem cell differentiation; interleukin-1-mediated signaling pathway; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	23198
	103554
	ENSG00000068878
	ENSMUSG00000040850
	Q14997
	Q5SSW2
	NM_014614
	NM_134013
	NP_055429
	NP_598774
	Wikidata
View/Edit Human	View/Edit Mouse

Proteasome activator complex subunit 4 is a protein that in humans is encoded by the PSME4 gene.