PSMF1

PSMF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2VT8, 4OUH
Identifiers
Aliases	PSMF1, PI31, proteasome inhibitor subunit 1
External IDs	OMIM: 617858; MGI: 1346072; HomoloGene: 38231; GeneCards: PSMF1; OMA:PSMF1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	1,189,415 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	151,586,106 bp
RNA expression pattern
	Top expressed in
	sperm; ; left testis; ; right testis; ; muscle of thigh; ; blood; ; gastrocnemius muscle; ; popliteal artery; ; tibial arteries; ; monocyte; ; islet of Langerhans;
	Top expressed in
	seminiferous tubule; ; spermatid; ; secondary oocyte; ; zygote; ; primary oocyte; ; blood; ; sciatic nerve; ; interventricular septum; ; fetal liver hematopoietic progenitor cell; ; spermatocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	proteasome binding; protein binding; endopeptidase inhibitor activity; protein homodimerization activity; protein heterodimerization activity;
Cellular component	cytoplasm; cytosol; membrane; nucleoplasm; endoplasmic reticulum; proteasome complex; proteasome core complex; perinuclear region of cytoplasm;
Biological process	regulation of cellular amino acid metabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; ubiquitin-dependent protein catabolic process; regulation of mRNA stability; positive regulation of canonical Wnt signaling pathway; protein polyubiquitination; stimulatory C-type lectin receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; MAPK cascade; Fc-epsilon receptor signaling pathway; NIK/NF-kappaB signaling; negative regulation of proteasomal protein catabolic process; anaphase-promoting complex-dependent catabolic process; T cell receptor signaling pathway; negative regulation of canonical Wnt signaling pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; Wnt signaling pathway, planar cell polarity pathway; negative regulation of endopeptidase activity; negative regulation of G2/M transition of mitotic cell cycle; protein deubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; transmembrane transport; regulation of transcription from RNA polymerase II promoter in response to hypoxia; post-translational protein modification; regulation of hematopoietic stem cell differentiation; interleukin-1-mediated signaling pathway; regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologs
	9491
	228769
	ENSG00000125818
	ENSMUSG00000032869
	Q92530; Q5QPM9
	Q8BHL8
NM_006814; NM_178578; NM_178579; NM_001323407; NM_001323408;
	NM_001323409; NM_001323410
	NM_144889; NM_212446; NM_001305244
NP_001310336; NP_001310337; NP_001310338; NP_001310339; NP_006805;
	NP_848693
	NP_001292173; NP_997611
	Wikidata
View/Edit Human	View/Edit Mouse

Proteasome inhibitor PI31 subunit is a protein that in humans is encoded by the PSMF1 gene.