PSRC1

PSRC1
Identifiers
Aliases	PSRC1, DDA3, FP3214, proline and serine rich coiled-coil 1
External IDs	OMIM: 613126; MGI: 1913099; HomoloGene: 49603; GeneCards: PSRC1; OMA:PSRC1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	109,283,186 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	108,295,547 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; ventricular zone; ; inferior olivary nucleus; ; inferior ganglion of vagus nerve; ; hippocampus proper; ; right frontal lobe; ; Brodmann area 9; ; substantia nigra; ; anterior cingulate cortex; ; primary visual cortex;
	Top expressed in
	zygote; ; secondary oocyte; ; ventricular zone; ; primary oocyte; ; genital tubercle; ; epiblast; ; condyle; ; calvaria; ; maxillary prominence; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; microtubule binding;
Cellular component	spindle microtubule; cytoskeleton; spindle; cytosol; microtubule cytoskeleton; spindle pole; midbody; cytoplasm; nucleoplasm;
Biological process	mitotic metaphase plate congression; negative regulation of cell growth; microtubule bundle formation; regulation of mitotic spindle organization; cell division; cell cycle; cellular process or phenomenon; positive regulation of transcription, DNA-templated; positive regulation of microtubule polymerization; positive regulation of cyclin-dependent protein serine/threonine kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	84722
	56742
	ENSG00000134222
	ENSMUSG00000068744
	Q6PGN9; Q5T2Z0
	Q9D0P7
NM_001005290; NM_001032290; NM_001032291; NM_032636; NM_001350237;
	NM_001350238; NM_001350239; NM_001350240; NM_001350241; NM_001350242; NM_001363309; NM_001394002; NM_001394003; NM_001394004; NM_001394005
	NM_001190161; NM_019976
NP_001005290; NP_001027462; NP_116025; NP_001337166; NP_001337167;
	NP_001337168; NP_001337169; NP_001337170; NP_001337171; NP_001350238
	NP_001177090; NP_064360
	Wikidata
View/Edit Human	View/Edit Mouse

Proline/serine-rich coiled-coil protein 1 is a protein that in humans is encoded by the PSRC1 gene.

This gene encodes a proline-rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.