Prostaglandin F receptor

PTGFR
Identifiers
Aliases	PTGFR, FP, Prostaglandin F receptor
External IDs	OMIM: 600563; MGI: 97796; HomoloGene: 741; GeneCards: PTGFR; OMA:PTGFR - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	78,540,701 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	151,543,267 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; gastric mucosa; ; tibial nerve; ; bronchial epithelial cell; ; synovial joint; ; smooth muscle tissue; ; stromal cell of endometrium; ; urethra; ; skin of hip; ; testicle;
	Top expressed in
	lumbar spinal ganglion; ; lower jaw; ; incisor; ; Meckel's cartilage; ; mandibular molars; ; right kidney; ; aortic valve; ; conjunctival fornix; ; urethra; ; female urethra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	prostaglandin F receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	cytoplasm; integral component of membrane; extracellular region; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; response to lipopolysaccharide; positive regulation of gene expression; response to estradiol; negative regulation of apoptotic process; cellular response to prostaglandin D stimulus; calcium-mediated signaling using intracellular calcium source; birth; positive regulation of cell population proliferation; signal transduction; inflammatory response; adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration;
	Sources:Amigo / QuickGO
Orthologs
	5737
	19220
	ENSG00000122420
	ENSMUSG00000028036
	P43088
	P43117
	NM_000959; NM_001039585
	NM_008966
	NP_000950; NP_001034674
	NP_032992
	Wikidata
View/Edit Human	View/Edit Mouse

Prostaglandin F receptor (FP) is a receptor belonging to the prostaglandin (PG) group of receptors. FP binds to and mediates the biological actions of prostaglandin F_2α (PGF_2α). It is encoded in humans by the PTGFR gene.