PTPMT1

PTPMT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3RGO, 3RGQ
Identifiers
Aliases	PTPMT1, DUSP23, MOSP, PLIP, PNAS-129, protein tyrosine phosphatase, mitochondrial 1, protein tyrosine phosphatase mitochondrial 1
External IDs	OMIM: 609538; MGI: 1913711; HomoloGene: 11973; GeneCards: PTPMT1; OMA:PTPMT1 - orthologs
EC number	3.1.3.48
Gene location (Human)
Chr.	Chromosome 11 (human)
End	47,573,461 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	90,748,389 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; putamen; ; left adrenal cortex; ; substantia nigra; ; Hypothalamus; ; right adrenal gland; ; caudate nucleus; ; right adrenal cortex; ; nucleus accumbens;
	Top expressed in
	left ventricle; ; interventricular septum; ; quadriceps femoris muscle; ; spermatid; ; white adipose tissue; ; testicle; ; peripheral nervous system; ; superior cervical ganglion; ; muscle tissue; ; muscle of thigh;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphoprotein phosphatase activity; phosphatase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; protein binding; phosphatidylglycerophosphatase activity; protein tyrosine phosphatase activity; hydrolase activity; protein tyrosine/serine/threonine phosphatase activity;
Cellular component	membrane; mitochondrion; mitochondrial inner membrane; nucleus;
Biological process	lipid metabolism; protein dephosphorylation; phospholipid biosynthetic process; cardiolipin biosynthetic process; peptidyl-tyrosine dephosphorylation; dephosphorylation; phosphatidylglycerol biosynthetic process; regulation of intrinsic apoptotic signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	114971
	66461
	ENSG00000110536; ENSG00000285206
	ENSMUSG00000063235
	Q8WUK0
	Q66GT5
	NM_175732; NM_001143984
	NM_025576
	NP_001137456; NP_783859
	NP_079852
	Wikidata
View/Edit Human	View/Edit Mouse

Protein tyrosine phosphatase, mitochondrial 1 is a protein in humans that is primarily coded by the gene PTPMT1 gene.