PTPRU

PTPRU
Identifiers
Aliases	PTPRU, FMI, PCP-2, PTP, PTP-J, PTP-PI, PTP-RO, PTPPSI, PTPRO, PTPU2, R-PTP-PSI, R-PTP-U, hPTP-J, protein tyrosine phosphatase, receptor type U, protein tyrosine phosphatase receptor type U
External IDs	OMIM: 602454; MGI: 1321151; HomoloGene: 4168; GeneCards: PTPRU; OMA:PTPRU - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	29,326,813 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	131,838,288 bp
RNA expression pattern
	Top expressed in
	canal of the cervix; ; olfactory zone of nasal mucosa; ; ectocervix; ; tibial nerve; ; sural nerve; ; nasal epithelium; ; right uterine tube; ; trigeminal ganglion; ; pars reticulata; ; pars compacta;
	Top expressed in
	ventricular zone; ; lens; ; neural layer of retina; ; primary visual cortex; ; molar; ; superior frontal gyrus; ; Region II of hippocampus proper; ; gastrula; ; cerebellar cortex; ; saccule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	beta-catenin binding; phosphoprotein phosphatase activity; phosphatase activity; protein binding; transmembrane receptor protein tyrosine phosphatase activity; hydrolase activity; protein tyrosine phosphatase activity; identical protein binding;
Cellular component	integral component of membrane; membrane; cell-cell junction; integral component of plasma membrane; cell junction; plasma membrane;
Biological process	cell differentiation; response to glucocorticoid; homotypic cell-cell adhesion; transmembrane receptor protein tyrosine phosphatase signaling pathway; negative regulation of cell migration; protein localization to cell surface; animal organ regeneration; canonical Wnt signaling pathway; negative regulation of cell population proliferation; dephosphorylation; cell adhesion; peptidyl-tyrosine dephosphorylation; protein dephosphorylation; cell-cell adhesion; negative regulation of canonical Wnt signaling pathway; positive regulation of cell-cell adhesion mediated by cadherin;
	Sources:Amigo / QuickGO
Orthologs
	10076
	19273
	ENSG00000060656
	ENSMUSG00000028909
	Q92729
	B1AUH1
	NM_001195001; NM_005704; NM_133177; NM_133178
	NM_001083119; NM_011214
	NP_001181930; NP_005695; NP_573438; NP_573439
	NP_001076588; NP_035344
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme that in humans is encoded by the PTPRU gene.