PTS (gene)

PTS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3I2B
Identifiers
Aliases	PTS, Pts, PTPS, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyl-tetrahydropterin synthase
External IDs	OMIM: 612719; MGI: 1338783; HomoloGene: 268; GeneCards: PTS; OMA:PTS - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	112,269,955 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	50,528,724 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; left adrenal cortex; ; right lobe of liver; ; right adrenal cortex; ; Pons; ; Hypothalamus; ; superior vestibular nucleus; ; glutes; ; biceps brachii; ; gingival epithelium;
	Top expressed in
	right kidney; ; granulocyte; ; proximal tubule; ; corneal stroma; ; medullary collecting duct; ; intercostal muscle; ; Paneth cell; ; brown adipose tissue; ; lumbar spinal ganglion; ; islet of Langerhans;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein homodimerization activity; metal ion binding; lyase activity; 6-pyruvoyltetrahydropterin synthase activity; identical protein binding;
Cellular component	cytoplasm; cytosol; mitochondrion;
Biological process	tetrahydrobiopterin biosynthetic process; cellular amino acid metabolic process; central nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	5805
	19286
	ENSG00000150787
	ENSMUSG00000032067
	Q03393
	Q9R1Z7
	NM_000317
	NM_011220
	NP_000308
	NP_035350; NP_001351417; NP_001351418; NP_001351419
	Wikidata
View/Edit Human	View/Edit Mouse

6-pyruvoyltetrahydropterin synthase, also known as PTS, is a human gene which facilitates folate biosynthesis.