PUM2

PUM2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3Q0Q, 3Q0R, 3Q0S
Identifiers
Aliases	PUM2, PUMH2, PUML2, pumilio RNA binding family member 2
External IDs	OMIM: 607205; MGI: 1931751; HomoloGene: 69183; GeneCards: PUM2; OMA:PUM2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	20,352,234 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	8,802,581 bp
RNA expression pattern
	Top expressed in
	epithelium of colon; ; middle temporal gyrus; ; ventricular zone; ; tibia; ; Achilles tendon; ; skin of thigh; ; cerebellar vermis; ; epithelium of nasopharynx; ; ganglionic eminence; ; bronchial epithelial cell;
	Top expressed in
	medial ganglionic eminence; ; Region I of hippocampus proper; ; human fetus; ; foot; ; cingulate gyrus; ; ciliary body; ; mesenteric lymph nodes; ; ventricular zone; ; entorhinal cortex; ; tail of embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; mRNA 3'-UTR binding; miRNA binding;
Cellular component	perinuclear region of cytoplasm; cytoplasmic stress granule; nuclear membrane; cytoplasm; cytosol;
Biological process	regulation of chromosome segregation; regulation of gene silencing by miRNA; positive regulation of RIG-I signaling pathway; regulation of translation; regulation of mRNA stability; positive regulation of gene silencing by miRNA; stress granule assembly; posttranscriptional regulation of gene expression; production of miRNAs involved in gene silencing by miRNA;
	Sources:Amigo / QuickGO
Orthologs
	23369
	80913
	ENSG00000055917
	ENSMUSG00000020594
	Q8TB72
	Q80U58
NM_001282752; NM_001282790; NM_001282791; NM_015317; NM_001352917;
	NM_001352918; NM_001352919; NM_001352920; NM_001352923; NM_001352925; NM_001352926; NM_001352927; NM_001352928; NM_001352929; NM_001352930
NM_001160219; NM_001160220; NM_001160221; NM_001160222; NM_030723;
	NM_001310519
NP_001269681; NP_001269719; NP_001269720; NP_056132; NP_001339846;
	NP_001339847; NP_001339848; NP_001339849; NP_001339852; NP_001339854; NP_001339855; NP_001339856; NP_001339857; NP_001339858; NP_001339859
NP_001153691; NP_001153692; NP_001153693; NP_001153694; NP_001297448;
	NP_109648
	Wikidata
View/Edit Human	View/Edit Mouse

Pumilio homolog 2 is an RNA-binding protein that in humans is encoded by the PUM2 gene.