PXDN

PXDN
Identifiers
Aliases	PXDN, COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO, peroxidasin, ASGD7
External IDs	OMIM: 605158; MGI: 1916925; HomoloGene: 33907; GeneCards: PXDN; OMA:PXDN - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	1,744,852 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	30,067,657 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; hair follicle; ; tendon of biceps brachii; ; visceral pleura; ; parietal pleura; ; saphenous vein; ; smooth muscle tissue; ; cartilage tissue; ; ascending aorta; ; adipose tissue;
	Top expressed in
	hand; ; epithelium of lens; ; renal corpuscle; ; umbilical cord; ; epididymis; ; Gonadal ridge; ; left lung lobe; ; medullary collecting duct; ; otic vesicle; ; external carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; extracellular matrix structural constituent; heme binding; interleukin-1 receptor antagonist activity; metal ion binding; peroxidase activity;
Cellular component	extracellular matrix; extracellular exosome; endoplasmic reticulum; extracellular space; extracellular region; collagen-containing extracellular matrix;
Biological process	extracellular matrix organization; response to oxidative stress; immune response; hydrogen peroxide catabolic process; cellular oxidant detoxification; negative regulation of cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	7837
	69675
	ENSG00000130508
	ENSMUSG00000020674
	Q92626
	Q3UQ28
	NM_012293
	NM_181395; NM_177804
	NP_036425
	NP_852060
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxidasin homolog is a protein that in humans is encoded by the PXDN gene.

Peroxidasin requires ionic bromine as a co-factor, making bromine an essential element for human life.