Pancuronium bromide

Pancuronium
Clinical data
AHFS/Drugs.com	Monograph
Pregnancy; category	AU: B2;
Routes of; administration	Intravenous
ATC code	M03AC01 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only); US: ℞-only;
Pharmacokinetic data
Bioavailability	NA
Protein binding	77 to 91%
Metabolism	Hepatic
Elimination half-life	1.5 to 2.7 hours
Excretion	Renal and biliary
Identifiers
	IUPAC name [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-Acetyloxy-10,13-dimethyl-2,16-bis(pyridin-1-yl)-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;
CAS Number	16974-53-1 ; bromide: 15500-66-0 ;
PubChem CID	441289;
IUPHAR/BPS	4001;
DrugBank	DB01337 ;
ChemSpider	25453 ;
UNII	J76UF062FS; bromide: U9LY9Y75X2 ;
KEGG	D00492 ;
ChEBI	CHEBI:7908 ;
ChEMBL	ChEMBL185073 ;
CompTox Dashboard (EPA)	DTXSID9023415 ;
ECHA InfoCard	100.035.923
Chemical and physical data
Formula	C35H60N2O4
Molar mass	572.875 g·mol−1
	InChI InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 ; Key:NPIJXCQZLFKBMV-YTGGZNJNSA-L ;
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Pancuronium (trademarked as Pavulon) is an aminosteroid muscle relaxant with various medical uses. It is used in euthanasia and is used in some states as the second of three drugs administered during lethal injections in the United States.

Clinical data


AHFS/Drugs.com	Monograph
Pregnancy category	AU: B2
Routes of administration	Intravenous
ATC code	M03AC01 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	NA
Protein binding	77 to 91%
Metabolism	Hepatic
Elimination half-life	1.5 to 2.7 hours
Excretion	Renal and biliary
Identifiers
IUPAC name [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-Acetyloxy-10,13-dimethyl-2,16-bis(pyridin-1-yl)-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
CAS Number	16974-53-1^Y bromide: 15500-66-0^Y
PubChem CID	441289
IUPHAR/BPS	4001
DrugBank	DB01337^Y
ChemSpider	25453^N
UNII	J76UF062FS bromide: U9LY9Y75X2^Y
KEGG	D00492^Y
ChEBI	CHEBI:7908^N
ChEMBL	ChEMBL185073^N
CompTox Dashboard (EPA)	DTXSID9023415
ECHA InfoCard	100.035.923
Chemical and physical data
Formula	C₃₅H₆₀N₂O₄
Molar mass	572.875 g·mol⁻¹
InChI InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1^N Key:NPIJXCQZLFKBMV-YTGGZNJNSA-L^N
^NY (what is this?) (verify)