Paraventricular thalamus

The paraventricular thalamus (PVT) is a midline thalamic nucleus with broad connectivity with other brain structures such as the hypothalamus, striatum, and amygdala. Rodent studies suggest that the PVT plays a role in modulating reward-seeking behavior, threat avoidance, and wakefulness via the hypothalamic-thalamic-striatal circuit, while contributing to the retrieval of fear and the regulation of stress through other circuits.

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