Paul Negulescu

Paul Negulescu
Born
Paul Adrian Negulescu

EducationUniversity of California, Berkeley (BSc, PhD)
Known forResearch of cystic fibrosis
AwardsWarren Alpert Foundation Prize (2018)
Shaw Prize in Life Science & Medicine (2022)
Wiley Prize (2023)
Breakthrough Prize in Life Sciences (2024)
Scientific career
FieldsCell biology
InstitutionsUniversity of California, Irvine
Aurora Biosciences
Vertex Pharmaceuticals
ThesisThe role and regulation of intracellular calcium during stimulus-secretion coupling in the parietal cell (1988)
Doctoral advisorTerry Machen

Paul Adrian Negulescu is an American–Romanian cell biologist. He is a Senior Vice President at American pharmaceutical company Vertex Pharmaceuticals. He received the 2022 Shaw Prize in Life science and medicine, together with Michael J. Welsh, for their work that uncovered the etiology of cystic fibrosis and developed effective medications.