Peanut allergen powder

Peanut allergen powder
Clinical data
Trade namesPalforzia
Other namesAR101, peanut allergen powder-dnfp, peanut (Arachis hypogaea) allergen powder-dnfp
AHFS/Drugs.comProfessional Drug Facts
License data
Routes of
administration
By mouth
ATC code
  • None
Legal status
Legal status
Identifiers
PubChem SID
DrugBank
UNII

Peanut allergen powder, sold under the brand name Palforzia, is an oral immunotherapy used for the treatment of children who have confirmed cases of peanut allergy. It is taken by mouth.

Peanut allergen powder is a powder that is manufactured from peanuts (Arachis hypogaea) and packaged in pull-apart color-coded capsules for dose escalation and up-dosing, and in a sachet for maintenance treatment. The accurate dosing of the pharmaceutical product allows use by people with allergies extreme enough to be seriously affected by a few milligrams too much.

The most common side effects of peanut allergen powder are abdominal pain, vomiting, nausea, tingling in the mouth, itching (including in the mouth and ears), cough, runny nose, throat irritation and tightness, hives, wheezing and shortness of breath and anaphylaxis. Peanut allergen powder should not be administered to those with uncontrolled asthma.

In January 2020, the FDA approved the drug to Aimmune Therapeutics for mitigating "allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanuts." It is the first drug approved for treating peanut allergies.