Pellotine

Pellotine
Names
Systematic IUPAC name
6,7-Dimethoxy-1,2-dimethyl-3,4-dihydro-1H-isoquinolin-8-ol
Other names
Peyotline; N-Methylanhalonidine; 8-Hydroxy-6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C13H19NO3/c1-8-11-9(5-6-14(8)2)7-10(16-3)13(17-4)12(11)15/h7-8,15H,5-6H2,1-4H3
    Key: NKHMWHLJHODBEP-UHFFFAOYSA-N
  • CC1C2=C(C(=C(C=C2CCN1C)OC)OC)O
Properties
C13H19NO3
Molar mass 237.299 g·mol−1
Melting point 110 to 113
Hazards
Lethal dose or concentration (LD, LC):
10 mg/kg (intravenous, dog)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pellotine, also known as peyotline or N-methylanhalonidine, is a tetrahydroisoquinoline alkaloid found in Lophophora species, in particular L. diffusa. It is the second most common alkaloid found in Lophophora williamsii (peyote). Pellotine is slightly sedative, and has been used by Native Americans as a constituent of peyote for sacramental purposes. It was reportedly once marketed for use as a sedative.